Products for Research Use Only

O-Glycoprotease

CAT: 0804-HY-E70565Size: 2 KUDry Ice: NoHazardous: No
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CAT#:0804-HY-E70565Size:2 KU
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-type O-glycosylated proteins. O-Glycoprotease sequence is from Akkermansia muciniphila, recombinantly expressed in E.coli, with a 6xHis tag at the C-terminus. The enzyme maintains high activity between pH 5.5-7.5 and is resistant to 1M NaCl, but is highly sensitive to EDTA (0.5 mM EDTA) and can be inhibited by Zn2+.
UNSPSC
12352204
Target
Endonuclease
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Inflammation/Immunology
Smiles
[O-Glycoprotease]
References & Citations
[1]Riley NM, et al. Deciphering O-glycoprotease substrate preferences with O-Pair Search. Mol Omics. 2022 Dec 5;18 (10) :908-922.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported