TMA-DPH (solution)

• Description:

  TMA-DPH (solution) is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm) . TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined[1][2][3].Solvent and concentration: DMSO: 10 mM

• Target:

  Fluorescent Dye

• Related Pathways:

  Others

• Field of Research:

  Others

• Smiles:

  C[N+] (C) (C) C1=CC=C (/C=C/C=C/C=C/C2=CC=CC=C2) C=C1.[O-]S (=O) (C3=CC=C (C) C=C3) =O

• Molecular Formula:

  C28H31NO3S

• Molecular Weight:

  461.62

• References & Citations:

  [1]Illinger D, et al. The kinetic aspects of intracellular fluorescence labeling with TMA-DPH support the maturation model for endocytosis in L929 cells. J Cell Biol. 1994 May;125 (4) :783-94.|[2]Illinger D, et al. A comparison of the fluorescence properties of TMA-DPH as a probe for plasma membrane and for endocytic membrane. Biochim Biophys Acta. 1995 Oct 4;1239 (1) :58-66.|[3]Benedetti A, et al. Plasma membrane fluidity in isolated rat hepatocytes: comparative study using DPH and TMA-DPH as fluorescent probes. J Gastroenterol Hepatol. 1989 May-Jun;4 (3) :221-7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  115534-33-3