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DTCOBG

CAT: 0804-HY-D2925Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-D2925Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DTCOBG (dTCO-SNAP) is a SNAP-tag reactive benzylguanine (BG) analogue specifically designed for the specific labeling of immune cells. dTCOBG forms a stable thioether bond through the cysteine at the active site of SNAP-tag and O6-benzylguanine, resulting in a covalent linkage. dTCOBG demonstrates unique advantages in the labeling of macrophages derived from ER-HoxB8: it only labels SNAP-tag + macrophages, with no background signal in the control group. dTCOBG can be used for click chemistry labeling[1].
Product Name Alternative
DTCO-SNAP
UNSPSC
12352005
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Smiles
O=C(NCC1=CC=C(C=C1)COC2=C3N=CNC3=NC(N)=N2)OC[C@@H]4O[C@H]5[C@H](CC/C([H])=C([H])/CC5)O4
Molecular Formula
C24H28N6O5
Molecular Weight
480.52
References & Citations
[1]Schöning J, et al. Toolbox of Clickable Benzylguanines for Labeling of HoxB8-Derived Macrophages via SNAP-Tag and Bioorthogonal Chemistry. Bioconjug Chem. 2025 Jan 15;36 (1) :34-43.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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