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Calcium 2-hydroxypropanoate (pentahydrate)

CAT: 0804-HY-B2227D-01Size: 100 gDry Ice: NoHazardous: No
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CAT#:0804-HY-B2227D-01Size:100 g
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Description
Calcium 2-hydroxypropanoate (pentahydrate) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Calcium 2-hydroxypropanoate (pentahydrate) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Calcium 2-hydroxypropanoate (pentahydrate) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2].
CAS Number
5743-47-5
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Concentration
10mM
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(C)O)O.[Ca].O.[0.5].[2.5]
Molecular Formula
C3H6O3.0.5Ca.2.5H2O
Molecular Weight
155.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Lucia Longhitano, et al. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype. Int J Mol Sci. 2022 Dec 20;24 (1) :24. |[2]Qiang Feng, et al. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nat Commun. 2022 Sep 6;13 (1) :4981.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

Chemical Information

Calcium Lactate Pentahydrate

See also: Calcium Cation (has active moiety).

CAS Number5743-47-5
PubChem CID165341
IUPAC Namecalcium;bis(2-hydroxypropanoate);pentahydrate
Molecular FormulaC6H20CaO11
Molecular Weight308.29
Topological Polar Surface Area126
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count11
Rotatable Bond Count0
Heavy Atom Count18
Formal Charge0
Complexity53
SMILES
CC(C(=O)[O-])O.CC(C(=O)[O-])O.O.O.O.O.O.[Ca+2]
InChI
InChI=1S/2C3H6O3.Ca.5H2O/c2*1-2(4)3(5)6;;;;;;/h2*2,4H,1H3,(H,5,6);;5*1H2/q;;+2;;;;;/p-2
InChIKey
HPVJXNNKHRNBOY-UHFFFAOYSA-L
Chemical Structure
2D Structure
2D structure of Calcium Lactate Pentahydrate
CAS: 5743-47-5
CID: 165341
Formula: C6H20CaO11
MW: 308.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight308.29
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count11
Rotatable Bond Count0
Exact Mass308.0631523
Monoisotopic Mass308.0631523
Topological Polar Surface Area126 Ų
Heavy Atom Count18
Formal Charge0
Complexity53.5
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count8
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
T205632-01Calcium 2-hydroxypropanoate pentahydrate
L2023-01Leucovorin Calcium Salt Pentahydrate (N-[4-[[ (2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl) methyl]amino]benzoyl]-L-glutamic Acid Calcium Salt, Calcium Levofolinate, Levoleucovorin Calcium, Folinic Acid Calcium Salt)
MBS6113391-01Leucovorin Calcium Salt Pentahydrate (N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid Calcium Salt, Calcium Levofolinate, Levoleucovorin Calcium, Folinic Acid Calcium Salt)
GE4641-1kgCalcium lactate pentahydrate
sc-482118Calcium folinate pentahydrate
MBS5782272Levomefolate calcium pentahydrate
C01295-01Calcium galactonate pentahydrate
TRC-L330400-5GLeucovorin Calcium Salt Pentahydrate
sc-281633Calcium L-lactate pentahydrate
LC-5393.1Calcium lactate pentahydrate p.A.

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