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Deltamethrin-d6

CAT: 0804-HY-B1971S1Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B1971S1Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Deltamethrin-d6 (Decamethrin-d6) is deuterium labeled Deltamethrin. Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control[1][2][3][4][5][6].
CAS Number
2483831-10-1
Product Name Alternative
Decamethrin-d6
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; Calcium Channel; Caspase; Endogenous Metabolite; Interleukin Related; Isotope-Labeled Compounds; NF-κB
Related Pathways
Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Smiles
N#C[C@H](C1=CC(OC2=CC=CC=C2)=CC=C1)OC([C@@H]3[C@@H](C3(C([2H])([2H])[2H])C([2H])([2H])[2H])/C=C(Br)\Br)=O
Molecular Formula
C22H13D6Br2NO3
Molecular Weight
511.24
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Lu Q, et al. Deltamethrin toxicity: A review of oxidative stress and metabolism [J]. Environmental research, 2019, 170: 260-281.|[3]Chi C C, et al. Effect of the pesticide, deltamethrin, on Ca2+ signaling and apoptosis in OC2 human oral cancer cells [J]. Drug and Chemical Toxicology, 2014, 37 (1) : 25-31.|[4]Kumar A, et al. Deltamethrin induced an apoptogenic signalling pathway in murine thymocytes: exploring the molecular mechanism [J]. Journal of Applied Toxicology, 2014, 34 (12) : 1303-1310.|[5]Rehman H, et al. The modulatory effect of deltamethrin on antioxidants in mice [J]. Clinica Chimica Acta, 2006, 369 (1) : 61-65.|[6]Hossain M M, et al. Neuromechanical effects of pyrethroids, allethrin, cyhalothrin and deltamethrin on the cholinergic processes in rat brain [J]. Life sciences, 2005, 77 (7) : 795-807|[7]Yang X, et al. The heart as a target for deltamethrin toxicity: Inhibition of Nrf2/HO-1 pathway induces oxidative stress and results in inflammation and apoptosis [J]. Chemosphere, 2022, 300: 134479.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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