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Thiacetazone (Standard)

CAT: 0804-HY-B1526R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1526R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thiacetazone (Standard) is the analytical standard of Thiacetazone. This product is intended for research and analytical applications. Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL[1].
CAS Number
104-06-3
Product Name Alternative
Thioacetazone (Standard) ; Amithiozone (Standard)
UNSPSC
12352005
Target
Antibiotic; Bacterial; Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
CC(NC1=CC=C(/C=N/NC(N)=S)C=C1)=O
Molecular Formula
C10H12N4OS
Molecular Weight
236.29
References & Citations
[1]J L Stigliani, et al. New Insights Into the Chemical Behavior of S-oxide Derivatives of Thiocarbonyl-Containing Antitubercular Drugs and the Influence on Their Mechanisms of Action and Toxicity. Ann Pharm Fr. 2019 Mar;77 (2) :126-135.|[2] P Khanna, et al. Characteristics of a Cytosolic Arylacylamidase Metabolizing Thiacetazone. J Pharmacol Exp Ther. 1992 Sep;262 (3) :1225-31.|[3]Anuradha Alahari, et al. Thiacetazone, an Antitubercular Drug That Inhibits Cyclopropanation of Cell Wall Mycolic Acids in Mycobacteria. PLoS One. 2007 Dec 19;2 (12) :e1343.|[4]C A Peloquin, et al. Pharmacokinetic Evaluation of Thiacetazone. Pharmacotherapy. Sep-Oct 1996;16 (5) :735-41.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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