Allantoic acid (Standard)

CAT: 0804-HY-B1514R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1514R-01Size:5 mg
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Description
Anagrelide (hydrochloride) (Standard) is the analytical standard of Anagrelide (hydrochloride) . This product is intended for research and analytical applications. Anagrelide hydrochloride (BL4162A) is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36 nM) . Anagrelide hydrochloride, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide hydrochloride inhibits bone marrow megakaryocytopoiesis. Anagrelide hydrochloride decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide hydrochloride is a platelet-lowering agent and plays in the antithrombopoietic action[1][2][3].
CAS Number
[99-16-1]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Purity
99.84
Smiles
NC(NC(C(O)=O)NC(N)=O)=O
Molecular Formula
C4H8N4O4
Molecular Weight
176.13
Precautions
H315, H319, H335
References & Citations
[1]Taherkhani A, et, al. Metabolomic Analysis of Membranous Glomerulonephritis: Identification of a Diagnostic Panel and Pathogenic Pathways. Arch Med Res. 2019 May; 50 (4) :159-169.|[2]Okumura I, et, al. Stereospecificity of conversion of uric acid into allantoic acid by enzymes of Canadida utilis. J Biochem. 1976 May;79 (5) :1013-9.|[3]Cai HL, et, al. Therapeutic efficacy of atypical antipsychotic drugs by targeting multiple stress-related metabolic pathways. Transl Psychiatry. 2017 May 16; 7 (5) :e1130.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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