Products for Research Use Only

Meglutol (Standard)

CAT: 0804-HY-B1189R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1189R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Meglutol (Standard) is the analytical standard of Meglutol. This product is intended for research and analytical applications. Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis) . Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases[1][2].
CAS Number
503-49-1
UNSPSC
12352100
Target
Autophagy; Endogenous Metabolite; HMG-CoA Reductase (HMGCR) ; Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
O=C(O)CC(C)(O)CC(O)=O
Molecular Formula
C6H10O5
Molecular Weight
162.14
References & Citations
[1]Leipnitz G, et al. Evidence that 3‐hydroxy‐3‐methylglutaric acid promotes lipid and protein oxidative damage and reduces the nonenzymatic antioxidant defenses in rat cerebral cortex[J]. Journal of neuroscience research, 2008, 86 (3) : 683-693.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards