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Travoprost-d7

CAT: 0804-HY-B0584S2Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B0584S2Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Travoprost-d7 (Fluprostenol isopropyl ester-d7) is deuterium labeled Travoprost. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension[1].
Product Name Alternative
Fluprostenol isopropyl ester-d7; AL6221-d7; Flu-Ipr-d7
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Prostaglandin Receptor
Related Pathways
GPCR/G Protein; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cardiovascular Disease
Smiles
O=C(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@H](COC2=CC=CC(C(F)(F)F)=C2)O)OC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
Molecular Formula
C26H28D7F3O6
Molecular Weight
507.59
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]M R Hellberg, et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J Ocul Pharmacol Ther. 2001 Oct;17 (5) :421-32.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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