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Olsalazine (Standard)

CAT: 0804-HY-B0174AR-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0174AR-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Olsalazine (Standard) is an orally active prodrug of 5-ASA. Olsalazine (Standard) can inhibit cells proliferation and induce apoptosis. Olsalazine (Standard) can reduce DAI and MPO activity and inhibit inflammatory cytokines levels. Olsalazine (Standard) can be used for the researches of cancer, inflammation and metabolic disease, such as colorectal cancer, inflammatory bowel disease (IBD) and hyperuricemic[1][2][3][4].
CAS Number
15722-48-2
UNSPSC
12352005
Target
Apoptosis; Reference Standards
Related Pathways
Apoptosis; Others
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Smiles
O=C(O)C1=C(O)C=CC(/N=N/C2=CC(C(O)=O)=C(O)C=C2)=C1
Molecular Formula
C14H10N2O6
Molecular Weight
302.24
References & Citations
[1]Brown WA, et al. 5-aminosalicyclic acid and olsalazine inhibit tumor growth in a rodent model of colorectal cancer. Dig Dis Sci. 2000 Aug;45 (8) :1578-84.|[2]Thapa D, et al. Cannabidiol Enhances the Therapeutic Efficacy of Olsalazine and Cyclosporine in a Murine Model of Colitis. Int J Mol Sci. 2025 Aug 16;26 (16) :7913.|[3]Niu Y, et al. Olsalazine Sodium Increases Renal Urate Excretion by Modulating Urate Transporters in Hyperuricemic Animals. Biol Pharm Bull. 2020 Nov 1;43 (11) :1653-1659.|[4]Itoh S, et al. Olsalazine inhibits cell proliferation and DNA methylation in canine lymphoid tumor cell lines. Pol J Vet Sci. 2021 Dec;24 (4) :515-523.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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