M7GTP

• Description :

  7-Methyl-guanosine-5'-triphosphate (m7GTP) is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate phosphorothioate analog is a potent cap-dependent translation inhibitor[1].

• CAS Number :

  [26554-26-7]

• Product Name Alternative :

  7-Methyl-guanosine-5'-triphosphate

• UNSPSC :

  12352005

• Target :

  Nucleoside Antimetabolite/Analog

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Metabolic Disease

• Solubility :

  10 mM in DMSO

• Smiles :

  O=[P](O[P](O[P](O)(O)=O)(O)=O)([O-])OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(N)=NC3=O)=C3[N+](C)=C2)O1

• Molecular Formula :

  C11H18N5O14P3

• Molecular Weight :

  537.21

• References & Citations :

  [1]Kowalska J, et al. Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation. Bioorg Med Chem Lett. 2009 Apr 1;19 (7) :1921-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported