M7GTP

CAT: 0804-HY-21586ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-21586ASize:1 Each
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Description
7-Methyl-guanosine-5'-triphosphate (m7GTP) is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate phosphorothioate analog is a potent cap-dependent translation inhibitor[1].
CAS Number
[26554-26-7]
Product Name Alternative
7-Methyl-guanosine-5'-triphosphate
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
O=[P](O[P](O[P](O)(O)=O)(O)=O)([O-])OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(N)=NC3=O)=C3[N+](C)=C2)O1
Molecular Formula
C11H18N5O14P3
Molecular Weight
537.21
References & Citations
[1]Kowalska J, et al. Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation. Bioorg Med Chem Lett. 2009 Apr 1;19 (7) :1921-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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