KRH-594

• Description :

  KRH-594 is an orally active angiotensin AT1 receptor antagonist. KRH-594 ameliorates the progression of diabetic nephropathy and hyperlipidaemia. KRH-594 inhibits cardiac hypertrophy[1].

• CAS Number :

  [167006-13-5]

• UNSPSC :

  12352005

• Target :

  Angiotensin Receptor

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Cardiovascular Disease; Metabolic Disease

• Smiles :

  O=C(C1=C(C(/N=C2SC(CC)=NN\2CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)=O)CCC1)O

• Molecular Formula :

  C25H23N7O3S

• Molecular Weight :

  501.56

• References & Citations :

  [1]Inada Y, et al. KRH-594, a new angiotensin AT1 receptor antagonist, ameliorates nephropathy and hyperlipidaemia in diabetic spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 2000 Apr;27 (4) :270-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  AT1 Receptor