Products for Research Use Only
RegisterLogin

Fonsartan

CAT: 0804-HY-19224Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-19224Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fonsartan (HR720) is an AT1 receptor antagonist. Fonsartan can be used for the study of myocardial infarction (MI) [1][2].
CAS Number
153235-15-5
Product Name Alternative
HR 720
UNSPSC
12352005
Target
Angiotensin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(C1=C(SC)N=C(CCCC)N1CC2=CC=C(C3=C(S(=O)(N([K])C(NCCC)=O)=O)C=CC=C3)C=C2)O[K]
Molecular Formula
C26H30K2N4O5S2
Molecular Weight
620.87
References & Citations
[1]Xia QG, et al. Significance of timing of angiotensin AT1 receptor blockade in rats with myocardial infarction-induced heart failure. Cardiovasc Res. 2001 Jan;49 (1) :110-7.|[2]Jin D, et al. Pharmacological profiles of a novel non-peptide angiotensin II type I receptor antagonist HR720 in vitro and in vivo. Jpn J Pharmacol. 1997 Nov;75 (3) :259-66.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
AT1 Receptor

Chemical Information

Fonsartan

an angiotensin II receptor antagonist; structure given in first source

CAS Number153235-15-5
PubChem CID11585346
IUPAC Namedipotassium;2-butyl-5-methylsulfanyl-3-[[4-[2-[(C-oxido-N-propylcarbonimidoyl)sulfamoyl]phenyl]phenyl]methyl]imidazole-4-carboxylate
Molecular FormulaC26H30K2N4O5S2
Molecular Weight620.9
Topological Polar Surface Area173
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count12
Heavy Atom Count39
Formal Charge0
Complexity852
SMILES
CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3S(=O)(=O)NC(=NCCC)[O-])C(=O)[O-])SC.[K+].[K+]
InChI
InChI=1S/C26H32N4O5S2.2K/c1-4-6-11-22-28-24(36-3)23(25(31)32)30(22)17-18-12-14-19(15-13-18)20-9-7-8-10-21(20)37(34,35)29-26(33)27-16-5-2;;/h7-10,12-15H,4-6,11,16-17H2,1-3H3,(H,31,32)(H2,27,29,33);;/q;2*+1/p-2
InChIKey
WGZNJDWXOFLZKQ-UHFFFAOYSA-L
Chemical Structure
2D Structure
2D structure of Fonsartan
CAS: 153235-15-5
CID: 11585346
Formula: C26H30K2N4O5S2
MW: 620.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight620.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count12
Exact Mass620.0931754
Monoisotopic Mass620.0931754
Topological Polar Surface Area173 Ų
Heavy Atom Count39
Formal Charge0
Complexity852
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes

Alternative Products

CatalogName
GTR19274008-01Fonsartan
T27347-01Fonsartan free acid

Popular Products