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Minopafant

CAT: 0804-HY-19099Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19099Size:1 Each
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Description
Minopafant (E 5880) is a PAF receptor antagonist. Minopafant can be used in studies of cerebral vasospasm following subarachnoid hemorrhage[1][2].
CAS Number
128420-61-1
Product Name Alternative
E 5880
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease; Cardiovascular Disease
Smiles
O=C(C1=C(C=CC=C1)OC)N(C(OC[C@H](OC)COC(N2CCC(CC2)OC(NCCCCCCCCCCCCCCCCCC)=O)=O)=O)CC3=CC=CC=[N+]3CC.[Cl-]
Molecular Formula
C46H73ClN4O9
Molecular Weight
861.55
References & Citations
[1]Hirashima Y, et al. Prevention of cerebrovasospasm following subarachnoid hemorrhage in rabbits by the platelet-activating factor antagonist, E5880[J]. Journal of neurosurgery, 1996, 84 (5) : 826-830.|[2]Hirashima Y, et al. Effect of a platelet-activating factor receptor antagonist, E5880, on cerebral vasospasm after aneurysmal subarachnoid hemorrhage--open clinical trial to investigate efficacy and safety. Neurol Med Chir (Tokyo) . 2001 Apr;41 (4) :165-75; discussion 175-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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