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Z-13752A

CAT: 0804-HY-18209Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-18209Size:1 Each
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Description
Z-13752A is a mercaptopropanoyl amino acid. Z-13752A inhibits NEP and ACE, with Ki values of 1.8 and 3.2 nM, respectively. Z-13752A decreases the arterial blood pressure and increases coronary blood flow. Z-13752A can be used in the research of coronary artery occlusion[1][2].
CAS Number
193420-09-6
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE) ; Neprilysin
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
SC[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(C3=NC=CS3)C=C2)C(O)=O)=O
Molecular Formula
C22H22N2O3S2
Molecular Weight
426.55
References & Citations
[1]Robl J A, et al. Recent advances in the design and development of vasopeptidase inhibitors[J]. Expert Opinion on Therapeutic Patents, 1999, 9 (12) : 1665-1677. |[2]Venugopal J. Pharmacological modulation of the natriuretic peptide system[J]. Expert Opinion on Therapeutic Patents, 2003, 13 (9) : 1389-1409.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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