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XL541

CAT: 0804-HY-18165Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-18165Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XL541 is a potent, selective S1P1 antagonist. XL541 inhibits GDP-GTP exchange. XL541 causes frank surface hemorrhaging of tumors. XL541 collaborates with Paclitaxel to exhibit antitumor activity against breast cancer and lung cancer[1].
CAS Number
1221878-06-3
UNSPSC
12352005
Target
LPL Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cancer
Smiles
FC1=CC=C(OC2=CC=C(NC([C@H]3N(C(CN4C=CN=N4)=O)C[C@H](CC5=CC=C(F)C=C5)C3)=O)C=C2)C=C1
Molecular Formula
C28H25F2N5O3
Molecular Weight
517.53
References & Citations
[1]Shankar G. Abstract# 3394: Selective disruption of tumor vessel architecture via inhibition of S1P1 with a novel small molecule, XL541. Cancer Research, 2009, 69 (9_Supplement) : 3394-3394.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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