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Piroctone

CAT: 0804-HY-180521Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-180521Size:1 Each
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Description
Piroctone is a potent hydroxypyridone antimicrobial agent that shows remarkable activity against fungi including Candida species. Piroctone inhibits hyphal induction of Candida albicans. Piroctone can efficiently chelate intracellular iron to induce relevant cytotoxicity in neuroblastoma cells. Piroctone can be used for antimicrobial and neuroblastoma research[1][2].
CAS Number
[50650-76-5]
UNSPSC
12352005
Target
Fungal
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
O=C1C=C(C)C=C(CC(CC(C)(C)C)C)N1O
Molecular Formula
C14H23NO2
Molecular Weight
237.34
References & Citations
[1]Sigle HC, et al. In vitro investigations on the mode of action of the hydroxypyridone antimycotics rilopirox and piroctone on Candida albicans. Mycoses. 2006 May;49 (3) :159-68.|[2]Sidarovich V, et al. Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells. Mol Pharmacol. 2015;87 (3) :513-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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