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LUF8100

CAT: 0804-HY-179607Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179607Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LUF8100 is a dual-target antagonist of CCR2/CCR5 with pKi values for CCR2 and CCR5 of 5.23 and 4.97 respectively. LUF8100 can be used for research on immune homeostasis and cancer[1].
CAS Number
2954281-30-0
UNSPSC
12352005
Target
CCR
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=S(NC1=CC(N2CCCCC2)=CC=C1)(C3=CC=C(Cl)C(C(F)(F)F)=C3)=O
Molecular Formula
C18H18ClF3N2O2S
Molecular Weight
418.86
References & Citations
[1]Essa K, et al. Combining AlphaFold with Focused Virtual Library Design in the Development of Novel CCR2 and CCR5 Antagonists. J Chem Inf Model. 2025 Nov 24;65 (22) :12398-12409.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR2; CCR5

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