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Anti-MRSA agent 40

CAT: 0804-HY-179059Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179059Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-MRSA agent 40 (Compound 7-8) is a potent agent against Methicillin-resistant Staphylococcus aureus (MRSA) . Anti-MRSA agent 40 exhibits significant antibacterial activity against MRSA2 and S. aureus ATCC 29213, with its MIC values being 1 μg/mL. Anti-MRSA agent 40 causes depolarization of the cell membrane, damages membrane integrity, and simultaneously increases the level of ROS within MRSA2, ultimately leading to cell lysis and death. Anti-MRSA agent 40 shows significant efficacy in the MRSA2 skin abscess model. Anti-MRSA agent 40 can be used for research on anti-MRSA infections[1].
UNSPSC
12352005
Target
Bacterial; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(O)C1=CC=C(/C=N\NC(CCCOC2=CC(OC(C=C(OC(C)(C)C=C3)C3=C4O)=C4C5=O)=C5C(C/C=C(C)/C)=C2OC)=O)C=C1
Molecular Formula
C36H36N2O9
Molecular Weight
640.68
References & Citations
[1]Tang Q, et al. Discovery of antibacterial and synergistic acylhydrazone functionalized α-mangostin derivatives against drug-resistant pathogens. Bioorg Chem. 2025 Oct 14;166:109108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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