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ABD0171

CAT: 0804-HY-178917Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178917Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABD0171 is an effective ALDH inhibitor. ABD0171 can increase ROS levels and induce cell apoptosis. ABD0171 exhibits significant cytotoxicity in various glioblastoma (GB) cell lines, with EC50 ranging from 2.47 to 11.78 µM. ABD0171 can be used for cancer research[1].
CAS Number
2595201-23-1
UNSPSC
12352005
Target
Aldehyde Dehydrogenase (ALDH) ; Apoptosis; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
CSC(C#CC(C)(N(CCOCC1=CC(C)=C(C=C1)C)C)C)=O
Molecular Formula
C19H27NO2S
Molecular Weight
333.49
References & Citations
[1]Jiménez R, et al. Targeting Retinaldehyde Dehydrogenases to Enhance Temozolomide Therapy in Glioblastoma. Int J Mol Sci. 2024 Oct 26;25 (21) :11512.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
C04943ABD0171

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