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UNC10415667

CAT: 0804-HY-178322Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178322Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UNC10415667 is a NSD2 degrader, with a DC50 values of 460 nM. UNC10415667 can be used for the study of cancers driven by NSD2 overexpression or dysregulation, such as multiple myeloma, acute lymphocytic leukemia, and prostate cancer[1].
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(C1=CC=C(N2)C(OCC2=O)=C1)N(C3CC3)CC4=CC=C(C(NC5=CC6=C(CN(C(C7=CC=C(C=O)C=C7)=O)CC6)C=C5)=O)C=C4
Molecular Formula
C37H32N4O6
Molecular Weight
628.67
References & Citations
[1]Robertson, K. C., Amann, S. J., Liu, T., et al. Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22. bioRxiv. 2025
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NSD2/MMSET/WHSC1

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CatalogName
GTR19281268-01UNC10415667

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