(R) -thioxo-Dxd

• Description :

  (R) -thioxo-Dxd is a Camptothecin (HY-16560) derivative. (R) -thioxo-Dxd can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. (R) -thioxo-Dxd can be used for research on tumors with high HER2 or TROP2 expression[1].

• CAS Number :

  [2806052-36-6]

• UNSPSC :

  12352005

• Target :

  ADC Payload

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  OCC(N[C@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=S)=NC6=CC(F)=C(C)C(CC1)=C62)=O

• Molecular Formula :

  C26H24FN3O5S

• Molecular Weight :

  509.55

• References & Citations :

  [1]Ao Li, et al. Ligand conjugate compounds as antitumor agents and their preparation, pharmaceutical compositions and use in the treatment of cancer. WO2022262789.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported