TPG-20A

• Description:

  TPG-20A is a SARS-CoV-2 main protease inhibitor with an IC50 of 27.8 nM. TPG-20A also inhibits MERS-CoV main protease. TPG-20A can be used for the research of infection, such as SARS-CoV-2[1].

• UNSPSC:

  12352005

• Target:

  SARS-CoV

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  O=C(C(N1)=CC2=C1C=CC=C2OC)N[C@@H](CC(C)C)C(NN(C(C(Cl)Cl)=O)CC3=CC=CNC3=O)=O

• Molecular Formula:

  C24H27Cl2N5O5

• Molecular Weight:

  536.41

• References & Citations:

  [1]Flury P, et al. Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity. J Med Chem. 2025 Sep 25;68 (18) :19339-19376.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported