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VU6080824

CAT: 0804-HY-178058Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178058Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU6080824 (Compound 5s), a derivative of ML-133 , is an inward-rectifier potassium channel (Kir2.1) inhibitor with an IC50 of 0.35 μM. VU6080824 has superior thallium flux and manual patch clamp (MPC) functional potency[1].
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Smiles
COC1=CC=C(C=C1)CNCC2=CC=C(C3=CC=CC(OC)=C3)C=C2
Molecular Formula
C22H23NO2
Molecular Weight
333.42
References & Citations
[1]Duncan RA, et al. Characterization of Next-Generation Inhibitors for the Inward-Rectifier Potassium Channel Kir2.1: Discovery of VU6080824. ACS Med Chem Lett. 2025 Aug 29;16 (9) :1762-1771.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Inwardly rectifying potassium channel

Alternative Products

CatalogName
GTR19263025-01VU6080824 HCl

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