C3 (sodium)

• Description :

  C3 sodium is an aptamer that binds to Erk2. C3 binds to the MAP kinase insert domain, a unique site on Erk1/2. Due to this recognition profile C3 inhibits Erk2 activation by its upstream kinase MKK1.

• UNSPSC :

  12352208

• Target :

  ERK

• Related Pathways :

  MAPK/ERK Pathway; Stem Cell/Wnt

• Field of Research :

  Cancer

• Smiles :

  [C3(sodium)]

• References & Citations :

  [1]Lennarz S, Heider E, Blind M, Mayer G. An aptamer to the MAP kinase insert region. ACS Chem Biol. 2015;10 (1) :320-327.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  No Development Reported