PrCP-7414
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No


PrCP-7414
Description :
PrCP-7414 is a prolylcarboxypeptidase (PRCP) inhibitor. PrCP-7414 can block the receptor tyrosine kinase (RTK) signaling pathway mediated by PRCP and the GPCR-RTK crosstalk. PrCP-7414 can inhibit cancer cells proliferation and induce apoptosis. PrCP-7414 can be used for the research of cancer, such as triple negative breast cancer (TNBC) [1].UNSPSC :
12352005Target :
Apoptosis; CarboxypeptidaseRelated Pathways :
Apoptosis; Metabolic Enzyme/ProteaseField of Research :
CancerSmiles :
C[C@@H](C1=CC=C(C2=CC=CC=C2)C=C1)[C@H](NC(C(C)(N)C)=O)C(N3[C@@H](CCC3)C(NC4=C5)=NC4=CC(Cl)=C5Cl)=OMolecular Formula :
C31H33Cl2N5O2Molecular Weight :
578.53References & Citations :
[1]Duan L, et al. Prolyl Carboxypeptidase Maintains Receptor Tyrosine Kinase Signaling and Is a Potential Therapeutic Target in Triple Negative Breast Cancer. Cancers (Basel) . 2022 Jan 31;14 (3) :739.Shipping Conditions :
Room temperatureScientific Category :
Reference compound1Clinical Information :
No Development ReportedCAS Number :
[1252037-41-4]

