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CCI17464

CAT: 0804-HY-177691Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177691Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCI17464 is a selective, orally active EP4 partial agonist with a pKi of 7.1. CCI17464 can be used in a Freund's complete adjuvant (FCA) acute rat inflammatory pain model and shows complete reversal of allergic reactions[1].
CAS Number
325780-75-4
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(CC1=CC=C(N2C(C3=C(C4=C(C(OCC)=C3C2)C=CC=C4)OCC)=O)C=C1)O
Molecular Formula
C24H23NO5
Molecular Weight
405.44
References & Citations
[1]Healy MP, et al. Discovery of {4-[4,9-bis (ethyloxy) -1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EP4 receptor partial agonist for the treatment of pain. Bioorg Med Chem Lett. 2018 Jun 1;28 (10) :1892-1896.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP

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