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Frenlosirsen

CAT: 0804-HY-177632Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177632Size:1 Each
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Description
Frenlosirsen is an antisense oligonucleotide targeted to IRF4. It is used for study of relapsed/refractory multiple myeloma (RRMM) .
CAS Number
2304711-81-5
Product Name Alternative
ION-935918; ION251
UNSPSC
12352208
Target
IFNAR
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
[Frenlosirsen]
Molecular Formula
C177H226N63O89P15S15
Molecular Weight
5605.63
References & Citations
[1]Alexander A. Tong, Silvia Vicenzi, Lara C. Avsharian, Joshua D. Hartman, Trung V. Tran, Ashni A. Vora, Robert A. Vescio, Barry A. Paul, Caitlin L. Costello, T. Jesse Kwoh, Leslie A. Crews; Abstract CT146: Safety, tolerability and molecular correlates of the IRF4-targeted antisense oligonucleotide frenlosirsen in patients with relapsed/refractory multiple myeloma: A phase 1a dose escalation trial. Cancer Res 15 April 2025; 85 (8_Supplement_2) : CT146.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 1

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