ALN-3133 (sodium)

CAT: 0804-HY-177614Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-177614Size:1 Each

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Description

ALN-3133 sodium is a siRNA that targets VEGF, and it is one of the siRNAs in ALN-VSP.ALN-VSP is a lipid nanoparticle formulation containing two siRNAs for kinesin spindle protein (KSP) and VEGF with potential antitumor activity.

Product Name Alternative

AD3133 (sodium)

UNSPSC

12352208

Target

VEGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

[ALN-3133(sodium)]

References & Citations

[1]COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 GENE. US20110015250A1|[2]Tabernero J, Shapiro GI, LoRusso PM, et al. First-in-humans trial of an RNA interference therapeutic targeted to VEGF and KSP in cancer patients with liver involvement. Cancer Discov. 2013;3 (4) :406-417.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 1

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