Products for Research Use Only
RegisterLogin

Emiltatug ledadotin

CAT: 0804-HY-177542Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-177542Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Emiltatug ledadotin (Emi-Le; XMT-1660) is a B7-H4-targeted antibody-drug conjugate (ADC). Emiltatug ledadotin consists of a tumor-specific anti-B7-H4 monoclonal antibody Emiltatug , a linker-payload system built on the novel Dolasynthen (DS) ADC platform (HY-177541), and achieves site-specific conjugation via GlycoConnect click chemistry. Emiltatug ledadotin inhibits the growth of B7-H4-positive cancer cells. Emiltatug ledadotin can be used for the study of B7-H4-overexpressing advanced solid tumors, particularly breast, ovarian, and endometrial cancers[1].
CAS Number
2855974-40-0
Product Name Alternative
Emi-Le; XMT-1660
UNSPSC
12352005
Target
Antibody-Drug Conjugates (ADCs)
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
[Emiltatugledadotin]
References & Citations
[1]Toader D, et al. Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody-Drug Conjugate for the Treatment of Cancer. Mol Cancer Ther. 2023 Sep 5;22 (9) :999-1012.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported

Related Products

CatalogName
HY-177541Ledadotin
HY-P990918-01Emiltatug

Alternative Products

CatalogName
GTR19273567-01Ledadotin
T9901A-375-01Emiltatug
GTR18608364-01Emiltatug Antibody
DHJ14807Research Grade Emiltatug
ICH5519-50mgEmiltatug Biosimilar - Research Grade
GTR18695692-01Emiltatug Human Monoclonal Antibody
A138016Emiltatug Biosimilar (Monoclonal, IgG1)
A137138Emiltatug Biosimilar (Monoclonal, IgG1-kappa)
MBS1881165-01Anti-B7-H4 (emiltatug biosimilar) mAb
MBS1881166-01Biotinylated Anti-B7-H4 (emiltatug biosimilar) mAb

Popular Products