BBL454

CAT: 0804-HY-177509Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-177509Size:1 Each

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Description

BBL454 (Compound 43) is a Cholecystokinin 2B (CCK2B) receptor agonist. BBL454 induces hyperactivity and improves memory in rat models while it has weak activity on the peripheral CCK2 receptor and no anxiogenic activity. BBL454 increases gastric acid output in anesthetised rat models. BBL454 can be used for diabetes research[1][2].

UNSPSC

12352211

Target

Cholecystokinin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Metabolic Disease

Smiles

CCCCCCC(CC(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N(C)[C@@H](CCCC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(N)=O)=O)=O)=O)=O)=O

Molecular Formula

C40H54N6O8

Molecular Weight

746.89

References & Citations

[1]Kalindjian SB, et al. Strategies for the design of non-peptide CCK2 receptor agonist and antagonist ligand. Curr Top Med Chem. 2007;7 (12) :1195-204. |[2]Bellier B, et al. New CCK2 agonists confirming the heterogeneity of CCK2 receptors: characterisation of BBL454. Naunyn Schmiedebergs Arch Pharmacol. 2004 Nov;370 (5) :404-13.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CCKBR

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GTR19273117-01	BBL454

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