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Sonvuterkib

CAT: 0804-HY-177132Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177132Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sonvuterkib (WX001) is a potent and orally active extracellular signal-regulated kinases (ERK) inhibitor with IC50 values of 1.4, 0.54 nM for ERK1, ERK2, respectively. Sonvuterkib inhibits cell proliferation. Sonvuterkib shows anticancer activity[1][2].
CAS Number
2890225-50-8
Product Name Alternative
WX001
UNSPSC
12352005
Target
ERK
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C1C2=C(C3(COC3)N1CC4=NC(C)=CC=C4)SC(C5=C(C)C=NC(NC6=CC=NN6C)=N5)=N2
Molecular Formula
C23H22N8O2S
Molecular Weight
474.54
References & Citations
[1]Ii, Yi, et al. Thiazole-lactam-spiroheterocyclic compounds and applications thereof. WO2023274256A1.|[2]WHO Drug Information. International Nonproprietary Names for Pharmaceutical.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK1; ERK2

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