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BDM88951

CAT: 0804-HY-176778Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176778Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BDM88951 (Compound 4 d) is a selective ERAP2 inhibitor with an IC50 of 19 nM. BDM88951 significantly inhibits antigen presentation. BDM88951 can be used for autoimmune diseases and cancers research[1].
CAS Number
2790420-60-7
UNSPSC
12352005
Target
Aminopeptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
COC(C=C1)=CC=C1C[C@H](N2C=C(N=N2)CNS(=O)(C3=CC=C(C4=CC=CC=C4)S3)=O)C(NO)=O
Molecular Formula
C23H23N5O5S2
Molecular Weight
513.59
References & Citations
[1]Camberlein V, et al. Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis. Angew Chem Int Ed Engl. 2022 Sep 26;61 (39) :e202203560.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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