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TH10184

CAT: 0804-HY-176262Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176262Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TH10184 is a NUDT5 inhibitor. TH10184 can be conjugated with VH032 and linker (HY-W001958) to synthesize PROTAC NUDT5 degrader DDD2 (HY-176261).
CAS Number
2271044-59-6
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
COC(C=C1C(O2)=NN=C2CN3C(C(N(C(N4C)=O)C)=O)=C4N=C3N5CCNCC5)=C(C=C1)C
Molecular Formula
C22H26N8O4
Molecular Weight
466.49
References & Citations
[1]Seher Alam, et al. A cell-based degrader assessment platform facilitates discovery of functional NUDT5 PROTACs. bioRxiv. June 19, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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