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BBDDL2204

CAT: 0804-HY-176135Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176135Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BBDDL2204 (compound 13) is a potent and selective EZH2 covalent inhibitor. BBDDL2204 inhibits EZH2Y641F with an IC50 of 2.5 nM[1].
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
CC1=C(C=C(C=C1C(NCC2=C(C=C(NC2=O)C)SC)=O)C3=C(C=C(C=C3)CN4CCOCC4)NC(C=C)=O)N(C5CCOCC5)CC
Molecular Formula
C37H47N5O5S
Molecular Weight
673.86
References & Citations
[1]Zhang Y, et al. Discovery of Highly Potent and Selective EZH2 Covalent Inhibitors via Incorporating Basic Amines. J Med Chem. 2025 May 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19257739-01BBDDL2204

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