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Rapaglutin A

CAT: 0804-HY-176050Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176050Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rapaglutin A is a glucose transporter (GLUT) inhibitor. Rapaglutin A is a pan-GLUT inhibitor of Class I isoforms GLUT1, GLUT3, and GLUT4 with an IC50 of 12 nM. Rapaglutin A has an inhibitory effect on A549 proliferation[1].
Product Name Alternative
RgA; JW11-D2
UNSPSC
12352005
Target
GLUT
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
COC(C=C1CC[C@@H]2C3=CC=CC(NC(CCC(N([C@H](C(N[C@@H](C(N([C@@](C(NCC(N(CC/C=C/C(OCC(C)(C(C(N4[C@](CCCC4)([H])C(O2)=O)=O)=O)C)=O)C)=O)=O)([H])[C@H](C)CC)C)=O)CC5=CC=CC=C5)=O)CC(C)C)C)=O)=O)=C3)=C(C=C1)OC
Molecular Formula
C64H87N7O14
Molecular Weight
1178.41
References & Citations
[1]Marnie Kotlyar, et al. Identification of Rapaglutin E as an Isoform-Specific Inhibitor of Glucose Transporter 1. ACS Chem Biol. 2025 Apr 14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T207258-01Rapaglutin A
T207118-01Rapaglutin E

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