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Lauric acid leelamide

CAT: 0804-HY-176008Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176008Size:1 Each
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Description
Lauric acid leelamide is the lauric acid (C-12) amide analog of Leelamine. Leelamine exhibits inhibitory activity against pyruvate dehydrogenase kinase (PDHK) with an IC50 value of 9.5 µM. Leelamine derivatives possess anti-inflammatory effects and can inhibit phospholipase A2 activity from various sources[1][2].
CAS Number
2095306-47-9
UNSPSC
12352211
Target
Drug Derivative
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
CC(C1=CC2=C([C@@]3([C@]([H])([C@](CNC(CCCCCCCCCCC)=O)(CCC3)C)CC2)C)C=C1)C
Molecular Formula
C32H53NO
Molecular Weight
467.77
References & Citations
[1]Aicher TD, et al. Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK) . Bioorg Med Chem Lett. 1999 Aug 2;9 (15) :2223-8.|[2]Wilkerson W, et al. Antiinflammatory phospholipase-A2 inhibitors. I[J]. European journal of medicinal chemistry, 1991, 26 (7) : 667-676.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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