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MLS000099089

CAT: 0804-HY-175970Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175970Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MLS000099089 is a 12/15-lipoxygenase (12/15-LOX) inhibitor with IC50 values of 3.4 μM and 10 μM for human and mice 12/15-LOX, respectively. MLS000099089 displays higher selectivity for 12/15-LOX over 5-LOX and COX-2. MLS000099089 can be used for the study of stroke[1].
CAS Number
423735-70-0
UNSPSC
12352005
Target
Lipoxygenase
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
OC1=C(C2=NNC(C3=C(C)C=CC=C3)=C2)C=C(C)C=C1
Molecular Formula
C17H16N2O
Molecular Weight
264.32
References & Citations
[1]Armstrong MM, et al. A potent and selective inhibitor targeting human and murine 12/15-LOX. Bioorg Med Chem. 2016 Mar 15;24 (6) :1183-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
12-LOX;15-LOX

Alternative Products

CatalogName
GTR19209331-01MLS000099089

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