Z55660043

CAT: 0804-HY-175763Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-175763Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Z55660043 is a Regulator of G protein signaling-14 (RGS14) inhibitor with an IC50 of 2.3 μM. Z55660043 selectively and non-covalently inhibits RGS14 GTPase-accelerating protein (GAP) activity without measurable cytotoxicity. Z55660043 can be used for central nervous system and metabolic disorders research[1].

CAS Number

865271-09-6

UNSPSC

12352005

Target

RGS Protein

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease; Neurological Disease

Smiles

COC1=CC=C(C=C1)OCC2=NN=C3SC=C(NN23)C4=CC(OC)=C(C=C4)OC

Molecular Formula

C20H20N4O4S

Molecular Weight

412.46

References & Citations

[1]Agogo-Mawuli PS, et al. Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14. bioRxiv [Preprint]. 2025 Aug 9:2025.06.11.659181.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Z55660043

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