Products for Research Use Only
RegisterLogin

IID432

CAT: 0804-HY-175741Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-175741Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
IID432 is a Trypanosoma cruzi Topoisomerase II inhibitor with an EC50 of 8 nM for Trypanosoma cruzi. IID432, a single dose of 25 mg/kg, can achieve relapse-free parasite clearance in mouse models of chronic Chagas disease. IID432 can be used for Chagas disease research[1].
UNSPSC
12352005
Target
Parasite; Topoisomerase
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
CC1=NC2=C(C=C(C=C2)N3CC[C@@H](C3)NC(CN4C=NC(C#N)=N4)=O)C=C1
Molecular Formula
C19H19N7O
Molecular Weight
361.40
References & Citations
[1]H Rachel Lagiakos, et al. Discovery of IID432: A highly efficacious and safe cyanotriazole inhibitor of Trypanosoma cruzi topoisomerase II for short-duration curative treatment of Chagas disease. ACS. 2025 Aug 20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II

Alternative Products

CatalogName
T210488-01IID432

Popular Products