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VU6032735

CAT: 0804-HY-175728-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-175728-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU6032735 is a potent and subtype-selective sperm-specific potassium channel 3 (SLO3) inhibitor with IC50 values of 165 nM (hSLO3) and 730 nM (mSLO3) . VU6032735 also inhibits sodium channel and L-type calcium channel VU6032735 can sustain high tissue exposure in the fertilized oviduct. VU6032735 can be used for the research of contraception[1].
UNSPSC
12352005
Target
Calcium Channel; Potassium Channel; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.26
Smiles
O=C(C1=CC=C(OCC2=CC=C(OC(F)(F)F)C=C2)C=C1)N3CCN(C4=NC=C(C(F)(F)F)C=C4)CC3
Molecular Formula
C25H21F6N3O3
Molecular Weight
525.44
References & Citations
[1]Kayla J. Temple, et al. ighly Potent and Subtype-Selective Sperm-Specific Potassium Channel SLO3 Inhibitors Display High Tissue Exposure in the Murine Female Reproductive Tract. ACS Pharmacol. Transl. Sci. 2025, 8, 9, 3281–3295
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
L-type calcium channel

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CatalogName
GTR19273096-01VU6032735

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