ArMan

CAT: 0804-HY-175421Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-175421Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

ArMan is an aryl mannoside ligand that can be chemically functionalized onto the surface of virus-like particles (VLPs) through click chemistry. VLPs can be used to target DC-SIGN dendritic cells, promote the selective co-binding of DC-SIGN and TLR7, and lead to a Th1-type immune response. VLP-ArMan-OvaI/II can significantly inhibit tumor growth in the mouse melanoma model[1].

UNSPSC

12352005

Target

Others

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

OC[C@H]([C@H]([C@@H]1O)O)O[C@@H]([C@H]1O)OC2=CC=C(CCNC(CCC#C)=O)C=C2

Molecular Formula

C19H25NO7

Molecular Weight

379.40

References & Citations

[1]Lensch V, et al. Carbohydrate-Lectin Interactions Reprogram Dendritic Cells to Promote Type 1 Anti-Tumor Immunity. ACS Nano. 2024 Oct 1;18 (39) :26770-26783.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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