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QPyN16Th

CAT: 0804-HY-175376Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175376Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
QPyN16Th is an N-palmitoylated cationic thiazolidine antibiotic. QPyN16Th is selectively active against the Gram-positive bavteria E. faecalis, S. aureus and MRSA with an MIC of 1.95 μM over gram-negative bacteria. QPyN16Th can induce membrane permeabilization and depolarization and ROS production in MRSA. QPyN16Th increases the survival of zebrafish model of intramuscular MRSA infection[1].
UNSPSC
12352005
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(N1C(C2=[N+](C=CC=C2)C)SCC1)CCCCCCCCCCCCCCC.[I-]
Molecular Formula
C25H43IN2OS
Molecular Weight
546.59
References & Citations
[1]Pious, A., et al., (2024) . Synthesis of cationic N-acylated thiazolidine for selective activity against Gram-positive bacteria and evaluation of N-acylation's role in membrane-disrupting activity. RSC medicinal chemistry.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19264586-01QPyN16Th

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