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XB2M54

CAT: 0804-HY-175348Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175348Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XB2M54 is a selective XIAP antagonist. XB2M54 inhibits NOD2-mediated inflammatory signaling. XB2M54 is an E3 ligase ligand. XB2M54 can be used for synthesis of PROTAC ERα Degrader-1.
CAS Number
1467165-30-5
UNSPSC
12352005
Target
IAP; Ligands for E3 Ligase; NOD-like Receptor (NLR)
Related Pathways
Apoptosis; Immunology/Inflammation; PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Others
Smiles
CN[C@H](C(N[C@@H]1C(N(C2=C(N([C@H]1C)C(C)=O)C=C(C#N)C=C2)CC3=C(C=CC4=C3C=CC=C4)OC)=O)=O)C
Molecular Formula
C29H31N5O4
Molecular Weight
513.59
References & Citations
[1]Shemorry A, et al. Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases. Cell Chem Biol. 2025 May 15;32 (5) :694-709.e35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOD2; XIAP

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CatalogName
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