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FAP-IN-6

CAT: 0804-HY-175330Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175330Size:1 Each
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Description
FAP-IN-6 (Compound 21) is a selectivity FAP inhibitor with an IC50 of 13 pM. FAP-IN-6 has a high metabolic stability. FAP-IN-6 labeled with 18F can be used as a positron emission tomography (PET) tracer. FAP-IN-6 can be used for microenvironment of cancers research[1].
UNSPSC
12352005
Target
FAP
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
O=C(C1=CC=NC2=CC=C(C=C21)N(CCCN3N=NC(COCCOCCOCCF)=C3)C)NCC(N4CCC[C@H]4C#N)=O
Molecular Formula
C30H39FN8O5
Molecular Weight
610.68
References & Citations
[1]Köchel R, et al. Novel [18F]Fluorine-Based PET Tracers with Polar But Nonbasic Linkers to Image the Fibroblast Activation Protein in the Microenvironment of Tumors. J Med Chem. 2025 Jul 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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