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PXR Ligand 3

CAT: 0804-HY-175267Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175267Size:1 Each
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Description
PXR Ligand 3 is a PXP ligand. PXR Ligand 3 can be used to synthesize PROTAC MI1013.
CAS Number
2733559-38-9
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; Pregnane X Receptor (PXR)
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
NC1=CC=C(S(=O)(C2=C(C)N(C3=CC(OC)=CC=C3OC)N=N2)=O)C=C1
Molecular Formula
C17H18N4O4S
Molecular Weight
374.41
References & Citations
[1]Kamaraj R, et al. Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation. J Med Chem. 2025 Jul 24;68 (14) :14271-14299.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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