Products for Research Use Only
RegisterLogin

4-TCPA

CAT: 0804-HY-175220Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-175220Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
4-TCPA is a potent VEGFR2 inhibitor. 4-TCPA induces apoptosis and cell cycle arrest, likely through inhibition of VEGFR2 and EGFR signaling with additional effects on the mTOR pathway. 4-TCPA can inhibit the vitality and proliferation of various cancer cell lines. 4-TCPA can be used for the study of cancers such as lung cancer, breast cancer and leukemia[1].
UNSPSC
12352005
Target
Apoptosis; EGFR; mTOR; VEGFR
Related Pathways
Apoptosis; JAK/STAT Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(Cl)C=C1)CN2N=NC(CNC3=C4C=C(OCCOC)C(OCCOC)=CC4=NC=N3)=C2
Molecular Formula
C25H28ClN7O5
Molecular Weight
541.99
References & Citations
[1]Dehghan-Nayeri MJ, et al. Synthesis, characterization, anti-proliferative, and apoptotic activity of a novel quinazoline-containing 1,2,3-triazole toward three human cancer cells. Sci Rep. 2025 Jul 1;15 (1) :20852.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MTOR; VEGFR2/KDR/Flk-1

Related Products

CatalogName
HY-W099255-01Ethyl 4,4,4,4',4',4'-hexafluoro-DL-valinate
HY-W7200064,4'-Diapo-ω, ω-carotene-4,4'-dial
HY-77910-014- (4-Bromophenyl) -4-hydroxypiperidine
HY-W0142264,4'-Dihydroxybenzophenone
HY-N90384',4''-Dihydroxyanigorootin
HY-W011927-014,4'-Sulfonyldiphenol
HY-W2697474,4'-Dimethoxyoctafluorobiphenyl
HY-W0119184,4'-Dichlorobenzophenone
HY-136064-014,4'-Dimethoxychalcone
HY-103610-014,4'-Dimethoxybenzil

Alternative Products

CatalogName
GTR19264300-014-TCPA
E109602General TCPa ELISA Kit
E109603Human TCPa ELISA Kit
EKU08171Alpha-Tocopherol (TCPa) ELISA Kit
RPU51270-01BSA Conjugated Alpha-Tocopherol (TCPa)
CAU32470-01Alpha-Tocopherol (TCPa) Polyclonal Antibody
E107812Bovine Bovine TCPa ELISA Kit
KLU0220GENLISA™ Alpha-Tocopherol (TCPa) ELISA
ELK7865-01TCPa (Alpha-Tocopherol) ELISA Kit
SDPA484Ge21-01OVA Conjugated Alpha-Tocopherol (TCPa)

Popular Products