TFSeB

CAT: 0804-HY-174419Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-174419Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

TFSeB is an orally active neuroprotective agent. TFSeB can reduce Streptozotocin (STZ) induced MAO-B and AChE activity. TFSeB exerts neuroprotective effects by increasing the expression of BCL-2, BDNF, NRF2, and decreasing the expression of BAX. TFSeB can reduce lipid peroxidation (TBARS) and reactive oxygen species (ROS) levels. TFSeB can reduce neuroinflammation. TFSeB can be used for research on Alzheimer’s disease[1].

CAS Number

3017240-62-6

UNSPSC

12352005

Target

Bcl-2 Family; Cholinesterase (ChE) ; Monoamine Oxidase; NF-κB; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

FC(F)(C1=CC=CC([Se]CC2CC3=C(O2)C=CC=C3)=C1)F

Molecular Formula

C16H13F3OSe

Molecular Weight

357.23

References & Citations

[1]Hall TK, et al. Neuroprotective Effects of a Benzofuran-Containing Selenium in a Mouse Alzheimer's Disease Model: Molecular, Biochemical, and Behavioral Analyses. ACS Chem Neurosci. 2025 Jul 2;16 (13) :2420-2434.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE; Bax; Bcl-2

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GTR19264335-01	TFSeB

TFSeB

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