CD39-IN-1

• Description:

  CD39-IN-1 (Compound 338) is a selective small-molecule CD39 inhibitor with an IC50 value of 68.7 nM. CD39-IN-1 shows anti-proliferative activity on tumor cells. CD39-IN-1 blocks CD39-mediated eATP hydrolysis in the ATP-adenosine pathway. CD39-IN-1 is promising for research of cancers[1].

• UNSPSC:

  12352005

• Target:

  NTPDase

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer

• Purity:

  99.86

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CN1C(C(NC2=CC=C(F)C(C(NC)=O)=C2C3=CN=C(OC4=CC=CC=C4)C=C3)=O)=CC5=CC=CC=C51

• Molecular Formula:

  C29H23FN4O3

• Molecular Weight:

  494.52

• References & Citations:

  [1]Wang S, et al. Discovery of a novel CD39 inhibitor by DNA-encoded library screening. Bioorg Med Chem Lett. 2025 Jun 2;127:130294.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported