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AW4

CAT: 0804-HY-173590Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-173590Size:1 Each
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Description
AW4 is a LSD1 inhibitor. AW4 inhibits LSD1 ΔTTAS activity in H3K4me2 demethylation assays. AW4 can be used for research of drug resistance[1].
CAS Number
2455469-18-6
UNSPSC
12352005
Target
Histone Demethylase
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
C1(C2=CC=CC(C3=CC=C([C@H]4[C@H](NC5CCNCC5)C4)C=C3)=C2)=CC=CC=C1
Molecular Formula
C26H28N2
Molecular Weight
368.51
References & Citations
[1]Waterbury AL, et al. Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance. Nat Commun. 2025 Apr 2;16 (1) :3156.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1

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